The global pharmaceutical market was estimated at USD 1.11 trillion in 2017 and projected to reach USD 1.43 trillion by 2020. In 2017, North America, Asia Pacific and Western Europe pharmaceutical market approximately accounted for 37%, 22% and 20% global market share respectively.
In 2017, top-10 global pharmaceutical companies generated sales of USD 437.257 billion accounting for roughly 40% global market share and top-15 global pharmaceutical companies generated sales of USD 568.617 billion accounting for 51% global market share. A comparative analysis of the top-15 organizations was used to develop a ranking for these companies.
The ranking model incorporated seven criteria for each organization with focus on revenues generated by pharmaceutical products and growth in pharmaceutical revenues (2016 – 2017). The criteria includes pharmaceutical revenues, annual pharmaceutical revenue growth, total R&D expense, total expense, total income, proportion of revenue from top three pharmaceutical products and revenue per employee. A score statistic was developed based on these selected criteria. Each company was assigned a score for each criteria and a weighted sum was used to arrive at the final score statistic. Pharmaceutical revenue received the highest weight (45%) while revenue from top 3 products (5%) receives the lowest. The score statistic represented the pharmaceutical financial health and diversity of product portfolio of each company.
F. Hoffmann-La Roche Ltd (Switzerland)
Hoffmann-La Roche (Roche) is a research-focused healthcare company that develops, manufactures and delivers innovative therapeutics and diagnostic instruments and tests. Roche offers medicine in oncology, diabetes, ophthalmology, neuroscience, immunology, and infectious diseases. In 2017, top 3 best-selling drugs include cancer treatments MabThera/Rituxan, Herceptin, and Perjeta.
Pfizer is a research-based pharmaceutical company engaged in the wellness, prevention and treatment for diseases across a broad range of therapeutic areas. The company operates through Innovative Health and Established Health business segments. Pfizer offers medicine in cardiology, oncology, and immunology. In 2017, top 3 best-selling drugs include Lyrica, Prevnar 13/Prevenar 13, and Ibrance.
AbbVie, is a research-based biopharmaceutical company that develops and markets advanced therapies focused on treating rheumatology, gastroenterology, dermatology, oncology, virology, neurological disorders and other metabolic related and critical conditions. In 2017, top 3 best-selling drugs include Humira, Imbruvica, and HCV.
Johnson & Johnson (U.S.)
Johnson & Johnson (J&J) is a pharmaceutical and consumer goods manufacturing companies and its subsidiaries are engaged in the research, development, manufacturing and selling of pharmaceuticals, medical devices and consumer health products. Johnson & Johnson offers medicine in Hepatitis C, HIV/AIDS, Arthritis, and digestive conditions. In 2017, top 3 best-selling drugs include Remicade, Stelara, and Invega Sustenna / Xeplion / Trinza / Trevicta.
Sanofi is a French pharmaceutical company involved in research, development, manufacturing and marketing of therapeutic solutions. Sanofi offer medicines in prescription and over the counter (OTC) categories having major drugs in central nervous system, cardiovascular, oncology, diabetes, internal medicine, and vaccines. In 2017, top 3 best-selling drugs include Lantus, Lovenox, and Aubagio.
Merck & Co. (U.S.)
Merck, research and development company, known as MSD outside the United States and Canada, offers health solutions through its prescription medicines, vaccines, biologic therapies and animal health products. Merck offers medicines in oncology, fertility, neurodegenerative diseases, and endocrinology. In 2017, top 3 best-selling drugs include Januvia / Janumet, Keytruda, and Gardasil / Gardasil 9.
Novartis is a global healthcare company based in Basel, Switzerland. The company’s portfolio includes innovative biological therapies and pharmaceuticals in several disease areas including oncology, cardiology, neurology, immunology, eye care, generic and bio-similar medicines. In 2017, top 3 best-selling drugs include Gilenya, Cosentyx, and Glivec.
Gilead Sciences (U.S.)
Gilead is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines. Gilead Sciences focused on virology, hepatology, hematology, oncology, cardiovascular, inflammation and respiratory diseases. In 2017, top 3 best-selling drugs include Harvoni, Epclusa, and Truvada.
GlaxoSmithKline is research-focused pharmaceutical company engaged in discovering, manufacturing and distributing pharmaceutical products including prescription medicines, vaccines and consumer healthcare. It offers medicines in cardiovascular disease, gynecology, diabetes, anti-infective, dermatology, and respiratory diseases. In 2017, top 3 best-selling drugs include Seretide/Advair, Triumeq, and Tivicay.
Amgen Inc. is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California that discovers and develops innovative therapies in both biopharmaceuticals and small molecule drugs. In 2017, top 3 best-selling drugs include Enbrel, Neulasta, and Aranesp.
Sources: SEC filings, companies websites, and annual reports.